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Article

Isolation of a chromosome 1 region affecting blood pressure and vascular disease traits in the stroke-prone rat model.

Hypertension (Dallas, Tex. : 1979) - 1 Dec 2003

Kato Norihiro, Nabika Toru, Liang Yi-Qiang, Mashimo Tomoji, Inomata Hyoe, Watanabe Takehiro, Yanai Kazuyuki, Yamori Yukio, Yazaki Yoshio, Sasazuki Takehiko

Abstract excerpt

Recently, a genome-wide screen has shown a major quantitative trait locus (QTL) for a stroke-associated phenotype on rat chromosome 1 (RNO1) independent of QTL for blood pressure (BP) in the stroke-prone spontaneously hypertensive rat (SHRSP) of a Heidelberg colony. However, it remains to be elucidated whether these observations reflect the existence of different genes predisposing to each of the disorders. To...

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PMID: 14623828
DOI: 10.1161/01.HYP.0000103161.27190.67

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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