Article
Genome-wide searches for blood pressure quantitative trait loci in the stroke-prone spontaneously hypertensive rat of a Japanese colony.
Journal of hypertension - 1 Feb 2003
Kato Norihiro, Mashimo Tomoji, Nabika Toru, Cui Zong Hu, Ikeda Katsumi, Yamori Yukio
Abstract excerpt
OBJECTIVES: Although several quantitative trait loci for blood pressure have been reported in stroke-prone spontaneously hypertensive rats (SHRSP), the results are not always concordant among different crosses. To evaluate potential confounding factors in linkage analysis, we performed genome-wide screens in F2 populations derived from SHRSP and Wistar-Kyoto rats of a Japanese colony. METHODS: Two F cohorts were...
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