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Article

Role of genetic factors in the etiopathogenesis of cerebrovascular accidents: from an animal model to the human disease.

Cellular and molecular neurobiology - 1 Oct 2004

Rubattu Speranza, Stanzione Rosita, Gigante Bruna, Volpe Massimo

Abstract excerpt

1. The present work summarizes current knowledge on the genetic susceptibility to stroke, a complex cardiovascular phenotypic trait due to both gene/environment and gene/ gene interactions. 2. Evidence for the existence of genes directly contributing to stroke occurrence was first obtained in the animal model of the stroke-prone (sp) spontaneously hypertensive rat (SHR) through a linkage analysis approach in F2...

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PMID: 15485132
DOI: 10.1023/b:cemn.0000036399.68720.bf

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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