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Article

Molecular evidence that the eukaryotic THO/TREX complex is required for efficient transcription elongation.

The Journal of biological chemistry - 3 Oct 2003

Rondón Ana G, Jimeno Sonia, García-Rubio María, Aguilera Andrés

Abstract excerpt

THO/TREX is a conserved eukaryotic complex formed by the core THO complex plus proteins involved in mRNA metabolism and export such as Sub2 and Yra1. Mutations in any of the THO/TREX structural genes cause pleiotropic phenotypes such as transcription impairment, increased transcription-associated recombination, and mRNA export defects. To assay the relevance of THO/TREX complex in transcription, we performed in...

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Identifiers

PMID: 12871933
DOI: 10.1074/jbc.M305718200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Molecular evidence that the eukaryotic THO/TREX complex is required for efficient transcription elongation.PMID 12871933Read ↗

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