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Article

Human hHpr1/p84/Thoc1 regulates transcriptional elongation and physically links RNA polymerase II and RNA processing factors.

Molecular and cellular biology - 1 May 2005

Li Yanping, Wang Xiaoling, Zhang Xiaojing, Goodrich David W

Abstract excerpt

Cotranscriptional loading of RNA processing factors onto nascent RNA facilitates efficient gene expression. Mechanisms responsible for coupling transcription and RNA processing are not well defined, but the Saccharomyces cerevisiae TREX complex provides an example. TREX is composed of the subcomplex THO that associates with RNA polymerase II and is required for normal transcriptional elongation. THO associates...

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Identifiers

PMID: 15870275
DOI: 10.1128/MCB.25.10.4023-4033.2005
PMCID: PMC1087710

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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