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Article

P53 and beta-catenin in colorectal cancer progression.

Current pharmaceutical design - 1 Jan 2003

Valentini Anna Maria, Pirrelli Michele, Renna Letizia, Armentano Raffaele, Caruso Maria Lucia

Abstract excerpt

Recently a possible cross talk about the relationship between p53 and beta-catenin has been suggested by the observation that colorectal cancers accumulating beta-catenin (as a result of APC mutations) also exhibit high frequency p53 mutations. Our aim was to evaluate the pattern of both the proteins and match these with the morphological changes in colorectal carcinogenesis. Immunohistochemical patterns of p53...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12871177
DOI: 10.2174/1381612033454216

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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