Article
Beta-catenin and the morphogenesis of colorectal cancer.
Virchows Archiv : an international journal of pathology - 1 Jul 2002
Brabletz Thomas, Jung Andreas, Kirchner Thomas
Abstract excerpt
Tumor growth and progression are morphogenetic processes that are characterized by ongoing changes in tumor structure and differentiation. These processes show similarities to morphogenesis in embryonic development, as supported by the fact that the main pathways regulating morphogenesis in early embryogenesis and organogenesis are directly or indirectly altered in most neoplasms. In colorectal adenocarcinomas,...
Topics
- Colorectal Neoplasms
- Cytoskeletal Proteins
- Humans
- Mutation
- Trans-Activators
- beta Catenin
