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Article

The PON1 M55L gene polymorphism is associated with reduced HDL-associated PAF-AH activity.

Journal of lipid research - 1 Oct 2003

Kakafika Anna I, Xenofontos Stavroula, Tsimihodimos Vasilis, Tambaki Afroditi P, Lourida Evangelia S, Kalaitzidis Rigas, Cariolou Marios A, Elisaf Moses, Tselepis Alexandros D

Abstract excerpt

The platelet-activating factor acetylhydrolase activity associated with high density lipoprotein (HDL-PAF-AH) may substantially contribute to the antioxidant, anti-inflammatory, and overall antiatherogenic effects of HDL. Two enzymes associated with HDL express PAF-AH catalytic activity, PAF-AH itself and paraoxonase-1 (PON1). The relative contribution of these enzymes in the expression of PAF-AH activity on HDL...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12867538
DOI: 10.1194/jlr.M300129-JLR200

Genes

PON1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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