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Article

Effect of PON1 polymorphism on HDL antioxidant potential is blunted with aging.

Experimental gerontology - 1 Aug 2007

Cherki Mounia, Berrougui Hicham, Isabelle Maxim, Cloutier Martin, Koumbadinga Gérémy Abdull, Khalil Abdelouahed

Abstract excerpt

Paraoxonase1 is a HDL-associated enzyme, which is responsible for their antioxidant property. This study was aimed to investigate the effect of PON1 [Q192R] and [L55M] genotypes on susceptibility of LDL and HDL to lipid peroxidation and on antioxidant activity of HDL as a function of aging. Seven...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17532162
DOI: 10.1016/j.exger.2007.04.006

Genes

PON1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17532162-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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