Article
Characterization of antioxidant/anti-inflammatory properties and apoA-I-containing subpopulations of HDL from family subjects with monogenic low HDL disorders.
Clinica chimica acta; international journal of clinical chemistry - 11 Jun 2011
Daniil Georgios, Phedonos Alexia A P, Holleboom Adriaan G, Motazacker Mohammad Mahdi, Argyri Letta, Kuivenhoven Jan Albert, Chroni Angeliki
Abstract excerpt
BACKGROUND: Genetic factors regulate both high-density lipoprotein (HDL) levels and functionality, thus affecting HDL antiatherogenic properties. We characterized the HDL antioxidant/anti-inflammatory properties and apoA-I-containing subpopulations in families with monogenic low HDL disorders. METHODS: Subjects with mutations in apolipoprotein A-I (apoA-I), ATP-binding cassette transporter A1 (ABCA1) or...
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