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Article

Histological heterogeneity and somatic mtDNA mutations in gastric intraepithelial neoplasia.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jun 2008

Rigoli Luciana, Di Bella Chiara, Verginelli Fabio, Falchetti Mario, Bersiga Alessandra, Rocco Alba, Nardone Gerardo, Mariani-Costantini Renato, Caruso Rosario A

Abstract excerpt

Somatic mutations of mitochondrial DNA (mtDNA) are associated with various types of human cancer. To elucidate their role in gastric carcinogenesis, we analyzed mutations in the displacement loop region of mtDNA in 24 paraffin-embedded gastric intraepithelial neoplasias (formerly dysplasia) from a high gastric cancer risk area in northern Italy. Helicobacter pylori infection was assessed by histological...

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PMID: 18425082
DOI: 10.1038/modpathol.2008.58

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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