Article
K-ras mutation in helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer.
International journal of cancer - 10 Feb 2002
Hiyama Toru, Haruma Ken, Kitadai Yasuhiko, Masuda Hiroshi, Miyamoto Masaki, Tanaka Shinji, Yoshihara Masaharu, Shimamoto Fumio, Chayama Kazuaki
Abstract excerpt
Mutations of an oncogene, K-ras, are associated with the development and progression of many types of human cancer. To elucidate the significance of K-ras mutations in gastric carcinogenesis, we examined K-ras mutations in gastric cancers and in Helicobacter pylori-associated chronic gastritis (H. pylori-CG), which is associated with an increased risk for the gastric cancer development. Specimens of gastric...
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