Article
Somatic mutation in mitochondrial DNA and nuclear microsatellite instability in gastric cancer.
Oncology reports - 1 Jan 2000
Hiyama Toru, Tanaka Shinji, Shima Hideyuki, Kose Kazuhiro, Tuncel Handan, Ito Masanori, Kitadai Yasuhiko, Sumii Masaharu, Yoshihara Masaharu, Shimamoto Fumio, Haruma Ken, Chayama Kazuaki
Abstract excerpt
It was reported that somatic mutations in the mitochondrial DNA (mtDNA) are associated with high-frequency microsatellite instability (MSI-H) of the nuclear in gastric cancers. However, no correlation between mtDNA mutations and nuclear MSI-H was found in colorectal, breast, and renal cancers. Th...
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