Article
Complex mechanism of site-specific DNA replication termination in fission yeast.
The EMBO journal - 1 Jul 2003
Codlin Sandra, Dalgaard Jacob Z
Abstract excerpt
A site-specific replication terminator, RTS1, is present at the Schizosaccharomyces pombe mating-type locus mat1. RTS1 regulates the direction of replication at mat1, optimizing mating-type switching that occurs as a replication-coupled recombination event. Here we show that RTS1 contains two cis-acting sequences that cooperate for efficient replication termination. First, a sequence of approximately 450 bp...
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