Article

Targeting platelet GPVI or GPIIb/IIIa only minimally affect acute inflammation and cardiac repair in experimental permanent myocardial infarction

2025-10-23

Abstract excerpt

<h4>Background</h4> Beyond their role in hemostasis, platelets are recognized as key regulators of inflammatory responses in ischemic diseases, including cardiac ischemia/reperfusion (I/R) injury with key roles of platelet membrane glycoproteins (GP)VI and IIb/IIIa. However, whether platelet-driven thrombo-inflammatory pathways affect acute inflammation and cardiac repair processes in permanent, non-reperfused my...

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Literature Corpus work: b12240f0-410f-51b2-9c7c-52b8add3b312
DOI: 10.1101/2025.10.22.683606

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