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Article

Expression profile of wild-type ETV6 in childhood acute leukaemia.

British journal of haematology - 1 Jul 2003

Patel Naina, Goff Lindsey K, Clark Taane, Ford Anthony M, Foot Nicola, Lillington Debra, Hing Sandra, Pritchard-Jones Kathy, Jones Louise K, Saha Vaskar

Abstract excerpt

Comparative expression analysis of wild-typeETV6 in the disease state showed an absence of expression in ETV6-CBFA2 acute lymphoblastic leukaemia (ALL) when compared with non-ETV6-CBFA2 ALL and acute myeloid leukaemia. Fluorescent in-situ hybridization and loss of heterozygosity studies showed that 73% of the ETV6-CBFA2 samples had a fully or partially deleted second ETV6 allele, explaining the lack of wild-type...

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Share to Core Binding Factor Alpha 2 Subunit

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ETS Translocation Variant 6 Protein

Share to Leukemia, Myeloid

Share to Loss of Heterozygosity

Share to Oncogene Proteins, Fusion

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Share to Proto-Oncogene Proteins c-ets

Source

Identifiers

PMID: 12823350
DOI: 10.1046/j.1365-2141.2003.04399.x

Genes

ETV6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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