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Article

Somatic heterozygous mutations in ETV6 (TEL) and frequent absence of ETV6 protein in acute myeloid leukemia.

Oncogene - 9 Jun 2005

Barjesteh van Waalwijk van Doorn-Khosrovani Sahar, Spensberger Dominik, de Knegt Yvonne, Tang Michelle, Löwenberg Bob, Delwel Ruud

Abstract excerpt

ETV6 (ets translocation variant gene 6) TEL (translocation ets leukemia), encoding a transcriptional repressor, is involved in various translocations associated with human malignancies. Strikingly, the nonrearranged ETV6 allele is often deleted or inactivated in cells harboring these translocations. Although ETV6 translocations are infrequent in acute myeloid leukemia (AML), mutations or deregulated expression of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ETS Translocation Variant 6 Protein

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Source

Identifiers

PMID: 15806161
DOI: 10.1038/sj.onc.1208588

Genes

ETV6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Somatic heterozygous mutations in ETV6 (TEL) and frequent absence of ETV6 protein in acute myeloid leukemia.PMID 15806161Read ↗

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