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Article

<i>ETV6</i> rearrangements are recurrent in myeloid malignancies and are frequently associated with other genetic events

8 Dec 2011

Abstract excerpt

ETV6 (TEL) rearrangements are favorable in pediatric acute lymphoblastic leukemia but are less well characterized in myeloid malignancies. We investigated 9,550 patients with myeloid disorders for ETV6 rearrangements by chromosome banding analysis and interphase fluorescence in situ hybridization. ETV6 rearrangements were identified in 51 of 9,550 (0.5%) patients (range, 19.2-85.3 years). Frequencies were in...

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PMID: 22162288
DOI: 10.1002/gcc.21918

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