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The Diverse Roles of ETV6 Alterations in B-Lymphoblastic Leukemia and Other Hematopoietic Cancers.

Advances in experimental medicine and biology - 1 Jan 2024

Monovich Alexander C, Gurumurthy Aishwarya, Ryan Russell J H

Abstract excerpt

Genetic alterations of the repressive ETS family transcription factor gene ETV6 are recurrent in several categories of hematopoietic malignancy, including subsets of B-cell and T-cell acute lymphoblastic leukemias (B-ALL and T-ALL), myeloid neoplasms, and mature B-cell lymphomas. ETV6 is essential for adult hematopoietic stem cells (HSCs), contributes to specific functions of some mature immune cells, and plays a...

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ETS Translocation Variant 6 Protein
Hematologic Neoplasms
Mutation
Oncogene Proteins, Fusion
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proto-Oncogene Proteins c-ets

Repressor Proteins

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PMID: 39017849
DOI: 10.1007/978-3-031-62731-6_13

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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