Article
Mutation screening of the Homer gene family and association analysis in schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jul 2003
Norton N, Williams H J, Williams N M, Spurlock G, Zammit S, Jones G, Jones S, Owen R, O'Donovan M C, Owen M J
Abstract excerpt
Homer proteins are a group of proteins that regulate group 1 metabotropic glutamate receptor function. As altered glutamate function has been implicated in many neuro psychiatric disorders, particularly schizophrenia, we have screened all three known Homer genes for sequence variation for use under the candidate gene association paradigm. We found seven SNPs, including three in exons. Of these, none was...
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