Article
Association of ARHGAP18 polymorphisms with schizophrenia in the Chinese-Han population.
PloS one - 1 Jan 2017
Guo Weiyun, Cai Yaqi, Zhang Hongxing, Yang Yongfeng, Yang Ge, Wang Xiujuan, Zhao Jingyuan, Lin Juntang, Zhu Jinfu, Li Wenqiang, Lv Luxian
Abstract excerpt
Numerous developmental genes have been linked to schizophrenia (SZ) by case-control and genome-wide association studies, suggesting that neurodevelopmental disturbances are major pathogenic mechanisms. However, no neurodevelopmental deficit has been definitively linked to SZ occurrence, likely due to disease heterogeneity and the differential effects of various gene variants across ethnicities. Hence, it is...
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