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Article

Screening the human protocadherin 8 (PCDH8) gene in schizophrenia.

Genes, brain, and behavior - 1 Aug 2002

Bray N J, Kirov G, Owen R J, Jacobsen N J, Georgieva L, Williams H J, Norton N, Spurlock G, Jones S, Zammit S, O'Donovan M C, Owen M J

Abstract excerpt

Abnormalities in synaptic connectivity and plasticity have been implicated in the pathophysiology of schizophrenia. Molecules involved in the development and maintenance of neural circuitry include the recently cloned protocadherins. Human protocadherin 8 (PCDH8) is homologous to 'arcadlin', a molecule shown to play a role in hippocampal synaptic function in the rat. The gene encoding PCDH8 maps to a region on...

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Source

Identifiers

PMID: 12884975
DOI: 10.1034/j.1601-183x.2002.10307.x

Genes

PCDH8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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