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Article

A family-based association study of DNA sequence variants in GRM7 with schizophrenia in an Indonesian population.

The international journal of neuropsychopharmacology - 1 Oct 2009

Ganda Clarissa, Schwab Sibylle G, Amir Nurmiati, Heriani Heriani, Irmansyah Irman, Kusumawardhani Agung, Nasrun Martina, Widyawati Ika, Maier Wolfgang, Wildenauer Dieter B

Abstract excerpt

We previously reported genome-wide significant linkage to chromosome 3p in a sib-pair family sample from Indonesia. A promising candidate gene within the linked region is the metabotropic glutamate receptor subtype 7 (GRM7), involved in glutamatergic neurotransmission. We genotyped 18 single nucleotide polymorphisms in GRM7 in the sample of 124 Indonesian sib-pair families that had provided the significant...

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Identifiers

PMID: 19638256
DOI: 10.1017/S1461145709990356

Genes

GRM7

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