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Article

A single nucleotide polymorphism in the HOMER1 gene is associated with sleep latency and theta power in sleep electroencephalogram.

PloS one - 1 Jan 2020

Pedrazzoli Mario, Mazzotti Diego Robles, Ribeiro Amanda Oliveira, Mendes Juliana Viana, Bittencourt Lia Rita Azeredo, Tufik Sergio

Abstract excerpt

Glutamate is the most excitatory neurotransmitter in the central nervous system and it is involved in the initiation and maintaining of waking and rapid-eye-movement (REM) sleep. Homer proteins act in the trafficking and/or clustering of metabotropic glutamate receptors, and polymorphisms in the HOMER1 gene have been associated with phenotypes related to glutamate signaling dysregulation. In this study, we report...

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Identifiers

PMID: 32645048
DOI: 10.1371/journal.pone.0223632
PMCID: PMC7347117

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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