Article
Association analysis of the RGS4 gene in Han Chinese and Scottish populations with schizophrenia.
Genes, brain, and behavior - 1 Oct 2005
Zhang F, St Clair D, Liu X, Sun X, Sham P C, Crombie C, Ma X, Wang Q, Meng H, Deng W, Yates P, Hu X, Walker N, Murray R M, Collier D A, Li T
Abstract excerpt
We investigated the RGS4 as a susceptibility gene for schizophrenia in Chinese Han (184 trios and 138 sibling pairs, a total of 322 families) and Scottish (580 cases and 620 controls) populations using both a family trio and case-control design. Both the samples had statistical power greater than 70% to detect a heterozygote genotype relative risk of >1.2 for frequent RGS4-risk alleles. We genotyped four single...
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