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Article

Resequencing and follow-up of neurexin 1 (NRXN1) in schizophrenia patients.

Schizophrenia research - 1 Apr 2011

Mühleisen Thomas W, Basmanav F Buket, Forstner Andreas J, Mattheisen Manuel, Priebe Lutz, Herms Stefan, Breuer Rene, Moebus Susanne, Nenadic Igor, Sauer Heinrich, Mössner Rainald, Maier Wolfgang, Rujescu Dan, Ludwig Michael, Rietschel Marcella, Nöthen Markus M, Cichon Sven

Abstract excerpt

Large rare deletions in NRXN1 increase the risk for schizophrenia. The aim of the present study was to determine whether small rare sequence changes in exons and splice sites contribute to the development of schizophrenia in a high-penetrance manner. Complete coding regions and splice sites were resequenced in 94 patients and 94 controls. Among the 16 rare sequence variants, two missense substitutions (E201G and...

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Source

Identifiers

PMID: 21288692
DOI: 10.1016/j.schres.2011.01.001

Genes

NRXN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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