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Article

CYP3A5 phenotype-genotype correlations in a British population.

British journal of clinical pharmacology - 1 Jun 2003

King Barry P, Leathart Julian B S, Mutch Elaine, Williams Faith M, Daly Ann K

Abstract excerpt

AIMS: To develop a polymerase chain reaction (PCR)-restriction fragment length polymorphism (RFLP)-based assay to genotype for hepatic CYP3A5 expression and to use this assay to study a British population. METHODS: CYP3A5-specific primers were designed with one including a base-pair mismatch to create a RsaI site in samples positive for G6986 (CYP3A5*3 allele) [correction]. Following PCR and RsaI digestion,...

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Share to Aged, 80 and over
Share to Cytochrome P-450 CYP3A
Share to Cytochrome P-450 Enzyme System

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heterozygote

Share to Microsomes, Liver

Share to Polymerase Chain Reaction

Share to Polymorphism, Restriction Fragment Length

Source

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Identifiers

PMID: 12814460
DOI: 10.1046/j.1365-2125.2003.01798.x
PMCID: PMC1884247

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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