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Article

The genetic determinants of the CYP3A5 polymorphism.

Pharmacogenetics - 1 Dec 2001

Hustert E, Haberl M, Burk O, Wolbold R, He Y Q, Klein K, Nuessler A C, Neuhaus P, Klattig J, Eiselt R, Koch I, Zibat A, Brockmöller J, Halpert J R, Zanger U M, Wojnowski L

Abstract excerpt

CYP3A proteins comprise a significant portion of the hepatic cytochrome P450 (CYP) protein and they metabolize around 50% of drugs currently in use. The dissection of the individual contributions of the four CYP3A genes identified in humans to overall hepatic CYP3A activity has been hampered by s...

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PMID: 11740341
DOI: 10.1097/00008571-200112000-00005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11740341-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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