Article
CYP3A5 variant allele frequencies in Dutch Caucasians.
Clinical chemistry - 1 Oct 2002
van Schaik Ron H N, van der Heiden Ilse P, van den Anker John N, Lindemans Jan
Abstract excerpt
BACKGROUND: Enzymes of the cytochrome P450 3A (CYP3A) family are responsible for the metabolism of >50% of currently prescribed drugs. CYP3A5 is expressed in a limited number of individuals. The absence of CYP3A5 expression in approximately 70% of Caucasians was recently correlated to a genetic p...
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