Article
Is the p53 gene mutation of prognostic value in hepatocellular carcinoma after resection?
Archives of surgery (Chicago, Ill. : 1960) - 1 Nov 2000
Jeng K S, Sheen I S, Chen B F, Wu J Y
Abstract excerpt
HYPOTHESIS: Mutant p53 gene has lost its tumor suppression function and is considered to be a very important step in hepatocellular carcinoma development. We propose that the mutant p53 gene plays a role in its invasiveness and prognosis after resection. DESIGN: A case-controlled study. SETTING: A referral center. PATIENTS: Seventy-nine consecutive patients who underwent surgical resection for hepatocellular...
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