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Article

Helper T-cell type 1 or type 2 function of xeno-MHC-restricted T-cell clones in a direct xenoantigen recognition.

Transplant immunology - 1 Jan 2000

Iida Yutaka, Iwata Hisashi, Mori Yoshio, Takagi Hisato, Nitta Toyoo, Kanetake Kazuto, Umeda Yukio, Hirose Hajime

Abstract excerpt

There have been several reports that xeno-MHC-restricted T-cells have a cytotoxic function through a direct xenoantigen recognition, but yet no report that they have a helper function. Previously we showed that both xeno-MHC-restricted CD4(+) and CD8(+) T-cells recognized xenoantigens directly in a mouse anti-rat combination. In this study, we investigated whether or not xeno-MHC-restricted T-cells had a helper...

Topics

Animals
Antigens, Heterophile
CD4-Positive T-Lymphocytes
CD8-Positive T-Lymphocytes
Cells, Cultured
Cytokines
Cytotoxicity, Immunologic
Enzyme-Linked Immunosorbent Assay
Flow Cytometry
Major Histocompatibility Complex

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Phenotype

Rats

T-Lymphocyte Subsets

T-Lymphocytes, Helper-Inducer

Source

Identifiers

PMID: 12799200
DOI: 10.1016/S0966-3274(02)00158-2

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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