Article
Direct recognition of rat MHC antigens on rat antigen-presenting cells by mouse CD4+ and CD8+ T cells and establishment of T cell clones exhibiting a direct recognition pathway.
Transplantation - 15 Mar 1997
Hirota T, Hirose H, Iwata H, Kanetake K, Murakawa S, Sasaki E, Takagi H, Bando M, Hamaoka T, Fujiwara H
Abstract excerpt
Alloantigens are recognized by T cells either through a direct pathway, which involves recognition of alloantigens expressed on allogeneic antigen-presenting cells (APC), or through an indirect pathway, which involves recognition of processed alloantigens presented by self APC. We investigated wh...
Topics
- Animals
- Antigen-Presenting Cells
- Antigens, Heterophile
- CD4-Positive T-Lymphocytes
- CD8-Positive T-Lymphocytes
- Cell Division
- Clone Cells
- Histocompatibility Antigens
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Phenotype
- Rats
- Rats, Inbred F344