Article
Immunosuppression of xenograft rejection in porcine kidney PK15 cells by porcine IL-18.
Experimental & molecular medicine - 31 Oct 2006
Choi Yun Sil, Kim Young Kwan, Shim Jung Hyun, Kim Eun Mi, Kang Hyung Sik, Yoon Do Young, Muneta Yoshihiro, Myung Pyung Keun
Abstract excerpt
Xenotransplantation, the transplantation of cells, tissues or organs between individuals of different species, would resolve the current shortage of organs, but rejection remains the major hurdle to successful xenotransplantation. In the present study, we analyzed mixed lymphocyte reactions (MLRs) and used 51Cr release assays in order to identify the proliferation and expansion of mouse CD8+ cytotoxic T...
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