Article
ENU mutagenesis in the mouse electrophoretic specific-locus test, 1. Dose-response relationship of electrophoretically-detected mutations arising from mouse spermatogonia treated with ethylnitrosourea.
Mutation research - 1 Aug 1991
Lewis S E, Barnett L B, Sadler B M, Shelby M D
Abstract excerpt
The mouse electrophoretic specific-locus test for induced germ-cell mutations, was used to determine the response of spermatogonial stem cells to a series of doses of the germ cell mutagen N-ethyl-N-nitrosourea (ENU). Male DBA/2J and C57B1/6J mice were treated with doses of 50, 100, 200 or 250 mg...
Topics
- Alleles
- Animals
- Dose-Response Relationship, Drug
- Electrophoresis, Starch Gel
- Ethylnitrosourea
- Female
- Kidney
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Mutagenesis