Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enzyme-activity mutants in Mus musculus. I. Phenotypic description and genetic characterization of ethylnitrosourea-induced mutations.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jul 2000

Pretsch W

Abstract excerpt

The specific activity of erythrocyte enzymes was measured to detect gene mutations in F(1)-offspring of male mice treatment with different doses (80, 160, or 250 mg/kg body weight) of ethylnitrosourea (ENU). Altogether 13,230 offspring were screened for 10 enzyme activities. Mutants with reduced activity as well as mutants with enhanced activity were found. Of the 36 independently observed mutations, 20 were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Crosses, Genetic
Share to Erythrocytes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Ethylnitrosourea

Share to Isomerases

Share to Mutagenesis

Share to Mutagens

Share to Oxidoreductases

Source

Identifiers

PMID: 10886019
DOI: 10.1007/s003350010103

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enzyme-activity mutants in Mus musculus. I. Phenotypic description and genetic characterization of ethylnitrosourea-induced mutations.PMID 10886019Read ↗

Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in plasma enzyme activities as novel organ-specific disease models.Semantic proximity Read ↗

Genotype-based screen for ENU-induced mutations in mouse embryonic stem cells.Semantic proximity Read ↗

Large-scale N-ethyl-N-nitrosourea mutagenesis of mice--from phenotypes to genes.Semantic proximity Read ↗

Characterization of two electrophoretic lactate dehydrogenase-A mutants in Mus musculus.Semantic proximity Read ↗

Glucose phosphate isomerase enzyme-activity mutants in Mus musculus: genetical and biochemical characterization.Semantic proximity Read ↗

Large scale ENU screens in the mouse: genetics meets genomics.Semantic proximity Read ↗

ENU mutagenesis in the mouse.Semantic proximity Read ↗

ENU mutagenesis in the mouse.Semantic proximity Read ↗

Genomewide two-generation screens for recessive mutations by ES cell mutagenesis.Semantic proximity Read ↗

Spectrum of ENU-induced mutations in phenotype-driven and gene-driven screens in the mouse.Semantic proximity Read ↗

Optimizing screening and mating strategies for phenotype-driven recessive N-ethyl-N-nitrosourea screens in mice.Semantic proximity Read ↗

Genetic, biochemical, and molecular characterization of nine glyceraldehyde-3-phosphate dehydrogenase mutants with reduced enzyme activity in Mus musculus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.