Article
Frequency and nature of specific-locus mutations induced in female mice by radiations and chemicals: a review.
Mutation research - 1 Dec 1992
Russell L B, Russell W L
Abstract excerpt
The inducibility of heritable mutations in female mammals has been measured in the mouse specific-locus test (SLT). For radiation-induced mutations, a large body of data has been accumulated that includes information about biological and physical factors that influence mutation yields. However, relatively few SLT studies in females have been conducted with chemicals to date. A single estimate of the spontaneous...
Topics
- Animals
- Female
- Male
- Mice
- Mosaicism
- Mutagens
- Mutation
- Oocytes
- Radiation Effects
- Spermatogonia
- Zygote