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Article

Sensitive detection of LOH events in a human cell line after C-ion beam exposure.

Journal of radiation research - 1 Dec 2002

Morimoto Shigeko, Honma Masamitsu, Yatagai Fumio

Abstract excerpt

A molecular analysis of the loss of heterozygosity (LOH) events in human cells after low-dose heavy-ion exposure could contribute to the sensitive detection of the genetic influences caused by high-LET radiation. We exposed human lymphoblastoid TK6-20C cells to 10 cGy of an accelerated C-ion (22 keV/microm) beam, and observed a 3.1-fold increase in the mutation frequency (MF) at the heterozygous thymidine kinase...

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Source

Identifiers

PMID: 12793752
DOI: 10.1269/jrr.43.s163

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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