Article
Detection of adaptive response at chromosome level.
Uchu Seibutsu Kagaku - 1 Nov 2004
Yatagai Fumio, Takayama Yuko, Inoue Masami, Honma Masamitsu, Iwaki Masaya
Abstract excerpt
We have just started the basic study to detect the genetic alterations at chromosome level as a result of radioadaptive response. The assay system is based upon the analysis of loss of heterozygosity (LOH) induced in human lymphoblastoid cell TK6, which were pre-irradiated with low-doses of ionizing radiation (IR) before the challenging irradiation. In our previous study, this analysis was shown to be very...
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