Article
Qualitative and quantitative difference in mutation induction between carbon- and neon-ion beams in normal human cells.
Uchu Seibutsu Kagaku - 1 Dec 2003
Suzuki Masao, Tsuruoka Chizuru, Kanai Tatsuaki, Kato Takeshi, Yatagai Fumio, Watanabe Masami
Abstract excerpt
We investigated the difference in cell-killing effect and mutation induction between carbon- and neon-ion beams in normal human cells. Carbon- and neon-ion beams were accelerated by the Riken Ring Cyclotron (RRC) at the Institute of Physical and Chemical Research in Japan. Cell-killing effect was measured as the reproductive cell death using the colony formation assay. Mutation induction at the HPRT locus was...
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