Article
Radiation specific patterns of loss of heterozygosity on chromosome 17q.
Mutation research - 30 May 2000
Giver C R, Grosovsky A J
Abstract excerpt
We and others have previously reported that the percentage of ionizing radiation-induced TK(-) mutants exhibiting loss of heterozygosity (LOH) is not significantly different from those occurring spontaneously. In order to search further for a distinguishing feature of the X-ray-induced spectrum, and to characterize mechanisms of chromosomal scale mutagenesis, we used detailed mapping information to analyze the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
