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Article

Model of robust induction of glomerulosclerosis in mice: importance of genetic background.

Kidney international - 1 Jul 2003

Ma Li-Jun, Fogo Agnes B

Abstract excerpt

BACKGROUND: Increasing evidence suggests that genetic background plays an important role in the development of progressive glomerulosclerosis. The remnant kidney model (RKM) of progressive renal disease has been used extensively in rats. However, C57BL/6 mice are resistant to glomerulosclerosis with RKM induced by either pole amputation or renal artery ligation. A pole resection protocol, applied in 129/Sv mice,...

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Identifiers

PMID: 12787428
DOI: 10.1046/j.1523-1755.2003.00058.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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