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Article

Genetic background strongly influences the severity of glomerulosclerosis in mice.

The Journal of veterinary medical science - 1 Oct 2010

Nishino Tomohiro, Sasaki Nobuya, Nagasaki Ken-Ichi, Ahmad Zulkifli, Agui Takashi

Abstract excerpt

The ICGN mouse strain is a glomerulosclerosis (GS) model that shows characteristic proteinuria, podocyte morphological abnormalities and increased extracellular matrix accumulation in the glomeruli, which are the final common pathology associated with a variety of kidney diseases leading to end-stage renal failure. Previously, we performed a quantitative trait locus (QTL) analysis to identify the causative genes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20484839
DOI: 10.1292/jvms.10-0144

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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