Article
C57BL/6 and 129/Sv mice: genetic difference to renal ischemia-reperfusion.
Journal of nephrology - 1 Jan 2000
Lu Xia, Li Na, Shushakova Nelli, Schmitt Roland, Menne Jan, Susnik Nathan, Meier Matthias, Leitges Michael, Haller Hermann, Gueler Faikah, Rong Song
Abstract excerpt
BACKGROUND: C57BL/6 and 129/Sv are the 2 most commonly used strains of mice in renal ischemia-reperfusion injury (IRI) studies, yet there are currently no studies that contrast differences in the degree of renal injury after ischemia-reperfusion. METHODS: To evaluate renal IRI in male C57BL/6 and 129/Sv mice, we performed unilateral clamping of the left renal pedicle for 45 minutes and compared the degree of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
