Article
Genetic predisposition to hypertension and microvascular injury in the remnant kidney model.
The Journal of laboratory and clinical medicine - 1 Sept 1993
Bidani A K, Griffin K A, Plott W, Schwartz M M
Abstract excerpt
Genetic factors have been implicated in the development and progression of glomerulosclerosis and nephron loss in both experimental animals and in humans. The influence of a differing genetic predisposition to hypertension was examined in the remnant kidney (RK) model of progressive glomerulosclerosis. Dahl salt-sensitive (S) and salt-resistant (R) rats fed a normal salt diet underwent either sham surgery or...
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