Article
Transcription-dependent recombination and the role of fork collision in yeast rDNA.
Genes & development - 15 Jun 2003
Takeuchi Yasushi, Horiuchi Takashi, Kobayashi Takehiko
Abstract excerpt
It is speculated that the function of the replication fork barrier (RFB) site is to avoid collision between the 35S rDNA transcription machinery and the DNA replication fork, because the RFB site is located near the 3'-end of the gene and inhibits progression of the replication fork moving in the opposite direction to the transcription machinery. However, the collision has never been observed in a blockless...
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