Article
Analysis of polymorphisms in the alpha-subunit of the olfactory G-protein Golf in lithium-treated bipolar patients.
Psychiatric genetics - 1 Jun 2003
Zill Peter, Malitas Petros N, Bondy Brigitta, Engel Rolf, Boufidou Fotini, Behrens Stefanie, Alevizos Basil E, Nikolaou Chryssoula K, Christodoulou George N
Abstract excerpt
OBJECTIVE: This study examines the alpha-subunit of the olfactory G-protein (G(olf)) as a possible candidate gene for bipolar disorder. The alpha-subunit of the G(olf) gene maps to a region on chromosome 18p that has been implicated in several linkage studies as a potential site of a bipolar disorder susceptibility loci. METHODS: We investigated whether two polymorphisms in the alpha-subunit of the G(olf) gene...
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