Article
Linkage disequilibrium analysis of G-olf alpha (GNAL) in bipolar affective disorder.
American journal of medical genetics - 20 Sept 1996
Tsiouris S J, Breschel T S, Xu J, McInnis M G, McMahon F J
Abstract excerpt
This study examines G-olf alpha as a possible candidate gene for susceptibility to bipolar affective disorder (BPAD) using the Transmission Disequilibrium Test (TDT). G-olf alpha, which encodes a subunit of a G-protein involved in intracellular signaling, maps within a region of chromosome 18 that has been implicated by two different linkage studies as a potential site of BPAD susceptibility loci. The expression...
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