Article
Linkage disequilibrium analysis of G-olf alpha (GNAL) in bipolar affective disorder.
American journal of medical genetics - 20 Sept 1996
Tsiouris S J, Breschel T S, Xu J, McInnis M G, McMahon F J
Abstract excerpt
This study examines G-olf alpha as a possible candidate gene for susceptibility to bipolar affective disorder (BPAD) using the Transmission Disequilibrium Test (TDT). G-olf alpha, which encodes a subunit of a G-protein involved in intracellular signaling, maps within a region of chromosome 18 tha...
Topics
- Alleles
- Bipolar Disorder
- Chromosome Mapping
- Chromosomes, Human, Pair 18
- Dinucleotide Repeats
- Female
- GTP-Binding Proteins
- Gene Frequency
- Humans
- Linkage Disequilibrium
- Macromolecular Substances
- Male
- Nuclear Family
- Polymorphism, Genetic