Article
Polymorphism of circadian clock genes and prophylactic lithium response.
Bipolar disorders - 1 Mar 2014
Rybakowski Janusz K, Dmitrzak-Weglar Monika, Kliwicki Sebastian, Hauser Joanna
Abstract excerpt
OBJECTIVES: The therapeutic action of lithium in bipolar mood disorder may be connected with its effect on biological rhythms. In the present study, an attempt was made to investigate an association between multiple single nucleotide polymorphisms (SNPs) and their haplotypes pertaining to four genes involved in regulation of biological rhythms [circadian locomotor output cycle kaput (CLOCK), aryl hydrocarbon...
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