Article
Human G(olf) gene polymorphisms and vulnerability to bipolar disorder.
Psychiatric genetics - 1 Jan 1998
Berrettini W H, Vuoristo J, Ferraro T N, Buono R J, Wildenauer D, Ala-Kokko L
Abstract excerpt
Two intronic polymorphisms of the human alpha subunit of the olfactory G-protein (G(olf)) are described. They were detected with single-stranded conformational polymorphism (SSCP) methods and confirmed by sequencing both strands. These single base pair (bp) substitutions occur in introns 3 (an A/...
Topics
- Alleles
- Bipolar Disorder
- Chromosomes, Human, Pair 18
- GTP-Binding Protein alpha Subunits
- GTP-Binding Proteins
- Genetic Predisposition to Disease
- Germany
- Heterotrimeric GTP-Binding Proteins
- Humans
- Introns
- Nerve Tissue Proteins
- Point Mutation
- Polymorphism, Single-Stranded Conformational
- RNA Splicing
- Reverse Transcriptase Polymerase Chain Reaction
- Schizophrenia