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Article

Association and linkage studies of candidate genes involved in GABAergic neurotransmission in lithium-responsive bipolar disorder.

Journal of psychiatry & neuroscience : JPN - 1 Sept 2000

Duffy A, Turecki G, Grof P, Cavazzoni P, Grof E, Joober R, Ahrens B, Berghöfer A, Müller-Oerlinghausen B, Dvoráková M, Libigerová E, Vojtĕchovský M, Zvolský P, Nilsson A, Licht R W, Rasmussen N A, Schou M, Vestergaard P, Holzinger A, Schumann C, Thau K, Robertson C, Rouleau G A, Alda M

Abstract excerpt

OBJECTIVE: To test for genetic linkage and association with GABAergic candidate genes in lithium-responsive bipolar disorder. DESIGN: Polymorphisms located in genes that code for GABRA3, GABRA5 and GABRB3 subunits of the GABAA receptor were investigated using association and linkage strategies. PARTICIPANTS: A total of 138 patients with bipolar 1 disorder with a clear response to lithium prophylaxis, selected...

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Identifiers

PMID: 11022400
PMCID: PMC1407742

Genes

GABRA3
GABRA5
GABRB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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